EFX Sports Lyzme 5 Fat Burner Review


  • Cayenne Pepper Extract is a proven thermogenic
  • Good dosage of Caffeine Anhydrous per serving
  • L-Tyrosine can improve your focus


  • No ingredients to suppress your appetite (eg. Glucomannan)
  • Contains 2 sources of stimulants (increased risk of jitters)
  • Not good value for money, in our honest opinion

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About The Product

Lyzme 5 is a fat burner supplement made by EFX Sports, released in 2018. It costs $44.99 for 30 serving containers, so it’s priced quite normally for a fat burner supplement.

From first glance, it looks to be a respectable fat burner; it contains some key thermogenic nutrients such as Cayenne Pepper Extract. But on a negative from our point of view, it contains 2 sources of stimulants, which increases your risk of jittery side effects.

We’ll expand on this as we analyze Lyzme 5’s nutrient profile in the next section. But first, we’ll tell you more about the company behind it.

Who Is EFX Sports? 

EFX Sports are best known for their patented form of Creatine Monohydrate ‘Kre-Alkalyn’, as well as their pre-workout, Training Ground PRE.

They’ve built a name for producing honest supplements. And we really respect that they try to provide honest products that don’t deceive anyone. But if we’re being honest, we don’t quite believe that they’ve managed to compete with the likes of Optimum Nutrition and MuscleTech in terms of reputation.

Anyway, that doesn’t matter while looking at their fat burner released in 2018, Lyzme 5. So let’s see which ingredients have been added to this product below…

Lyzme 5 Ingredients Explained

Lyzme 5 contains 10 main ingredients overall, which is on the border of what we consider to be acceptable; from experience, we believe that supplements containing more than 10 nutrients are often under-dosed.

From first glance, it seems like EFX Sports have spent most of their budget on dosing Lyzme 5 (the ingredient) well.

In fairness, this makes sense, as the whole product is named off this 1 ingredient. However, we’re concerned that tried-and-tested thermogenics, such as Cayenne Pepper Extract, have been under-dosed.

Anyway, we’ll expand on this as we take you through each nutrient in EFX Sport’s Lyzme 5. By the end of this review, you’ll have a good idea of how safe and effective this fat burner really is.


Here’s Everything You Need To Know:

Lyzme 5

In case you’re wondering, this is the ingredient that EFX Sports has named this fat burner after. It’s basically a patented form of ‘Trimethylammonium-methyl-glycine-methionine with nicotinic acid & folate’.

You’re probably thinking to yourself ‘what the f*ck did you just say?!’. So in simple terms, it’s an ingredient that EFX Sports have put together and made sure that no other company can copy.

As Lyzme 5 is a fat burner supplement, it shouldn’t come as a surprise that this ingredient is designed to promote fat loss. However, while EFX Sports are confident in its ability, there haven’t been enough reliable studies to prove that it’s reliable at this moment in time (in our honest opinion).

*Update* We’ve received information from Dr Jeff Golini of EFX Sports that Lymze 5 is able to break-up body fat and transport it via the bloodstream; this is believed to encourage your body to burn fat for energy. So apologies if we misunderstood this ingredient, it certainly sounds capable of packing a punch!

We would still like to keep an eye on future clinical studies so the effectiveness of this nutrient is re-inforced in the future.


Even those that don’t know much about supplements will have heard about Taurine before; this is because it’s commonly found in energy drinks.

Not only that, due to its presence in energy drinks, Taurine is also mistakenly believed to be a stimulant. However, Taurine has no effect on your energy levels.

So what does it do? Well, Taurine has shown to be capable of preventing cramping during exercise, so it can be a useful ‘bonus’ addition to a pre-workout supplement.

Unfortunately, though, we don’t consider this to be a necessary addition to EFX Sports’s fat burner, Lyzme 5, as it has no effect on fat loss. We would have much preferred to see a more useful nutrient such as Green Tea Extract here.


When it comes to raising your energy levels on a cut, Caffeine is definitely a great option – as long as you don’t consume too much at once.

The good news is that EFX Sports has added a pretty good dosage of Caffeine per capsule; Lyzme 5 has an overall Caffeine dosage of 280mg, which split into 3 capsule servings, equals around 93mg per serving.

So we’re pretty confident that Lyzme 5 will offer enough of a ‘kick’ while you cut calories (and potentially carbs) from your diet in order to lose body fat. But saying that, we probably wouldn’t recommend consuming much coffee or tea while taking Lyzme 5 either, or risk suffering jittery side effects.


L-Tyrosine is a ‘brain booster’ ingredient, so it’s better suited to nootropics and pre-workout supplements. But as an improvement in cognition isn’t the main reason for buying a fat burner, we don’t think this is a necessary addition to Lyzme 5.

Ultimately, we would have preferred to have seen a thermogenic nutrient instead here. Something like Green Tea Extract that’s tried-and-tested to promote fat loss would have been an ideal replacement for L-Tyrosine in Lyzme 5 here.



We mentioned earlier that EFX Sports had done well to dose Caffeine well in Lyzme 5. But they’ve slightly ruined things by adding another stimulant in the form of Theobromine; this stimulant alongside Caffeine increases your risk of suffering jittery side effects and energy crashes.

For this reason, we prefer to consume fat burner supplements that only contain 1 stimulant in a sensible dosage – to stay safe.

Beta Sitosterol Complex

We must be getting old and behind the times, because this is the first time that we’ve seen Beta-Sitosterol Complex in any fat burner.

What is it? Well, Beta-Sitosterol Complex is known for being beneficial for prostate health in men. Some studies have even shown that it might help to fight against hair loss too.

However, one thing that Beta-Sitosterol Complex simply isn’t proven to do, is promote fat loss. And as Lyzme 5 is a fat burner supplement, it simply isn’t a reliable addition to help you shed body fat here.

Cayenne Pepper Extract

Finally, a thermogenic nutrient that’s shown to work! You can’t argue with this one. Try eating a Cayenne Pepper and see what happens – your mouth will start burning, which is the same effect that most chili peppers have.

Why? Because chili peppers such as Cayenne Pepper contain high amounts of capsaicin, which is responsible for their ‘spice’. Now, capsaicin has proven to boost your metabolic rate, helping you in the battle to lose body fat and get shredded.

But the bad news is that EFX Sports has slightly under-dosed Cayenne Pepper Extract in Lyzme 5. There’s only 30mg in this fat burner, while a dosage of around 100mg is more effective in our honest opinion.

White Willow Extract 

We’ve seen this added to a few fat burners in the past, but we’re never quite sure why.

White Willow Extract contains a salicin, which is believed to be quite similar to aspirin, so it’s supposed to be pain-reliving to a degree. It also contains natural anti-inflammatory properties too, which might benefit your health in a similar way to turmeric.

However, there hasn’t been enough studies to show that White Willow Extract can promote fat loss. So we consider this to be an unreliable addition to Lyzme 5 here.

Hesperidin Complex

In case you’re wondering, Hesperidin is a flavonoid naturally found in orange peels. It’s believed to help improve blood circulation and might even have ‘brain-boosting’ properties too.

However, studies have failed to show that Hesperidin has any effect on fat loss or cholesterol levels; a study by Demonty et al is probably the most significant.

For this reason, we don’t believe that Hesperidin is a good addition to Lyzme 5 here. A proven thermogenic such as Green Tea Extract would have definitely been more beneficial.


This is the same ginger that you’ve cooked with and added to your meals. This nutrient has natural anti-inflammatory properties and has even shown to help treat the common cold too. So you can’t argue that Ginger is good for your general health.

Now, the fact that Ginger is being added to fat burners is interesting; there have been studies that have shown it to be capable of inducing thermogenesis. But in the same studies, it had no effect on total resting energy expenditure, meaning it didn’t really promote fat loss.

For this reason, Ginger is highly unreliable in our honest opinion. As we mentioned before though, Ginger is definitely beneficial to your general health, so it’s a useful ‘bonus’ addition to Lyzme 5 here.


See Your Best Options In Our
» Top 3 Fat Burners Page «

Lyzme 5 Side Effects

Not much is known about the ingredient Lyzme 5, so we’re unable to confirm whether it causes any side effects at the time of writing this review.

However, one thing that concerns us personally, is that EFX Sport’s Lyzme 5 contains 2 stimulants; this increases your risk of suffering from jitters and energy crashes. So we always try to choose fat burners that contain only 1 stimulant in a sensible dosage.

Here are the potential side effects from taking Lyzme 5: 

  • Jitters (Contians more than 1 stiumulant)
  • Energy Crashes (Contians more than 1 stiumulant)

Lyzme 5 Review Conclusion

Lyzme 5 is clearly a respectable fat burner from a respectable supplements company. We’ll be keeping an eye on whether there are more studies conducted on the patented ingredient, Lyzme 5.

However, for now, we’re unable to state whether Lyzme 5 (the ingredient) is a reliable fat burning nutrient. This is a problem, as this is the highest dosed nutrient in EFX Sports’ fat burner Lyzme 5 (which makes sense, since this product is named after the ingredient).

There are some positives though. Cayenne Pepper Extract is included, which is a proven thermogenic, while Ginger is known for its health-boosting properties too.

Dr Jeff Golini was personally able to offer some help in understanding EFX Sports’ Lymze 5 ingredient, which was extremely appreciated. It’s great to see companies actively engaging with their fans and providing clarity on issues, and long may this continue.


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3 thoughts on “EFX Sports Lyzme 5 Fat Burner Review”

  1. thanks for this review it helpd me decide which product to buuy in the end. Appreciate the help leanbulking!

    • Hey Jeff,

      It’s great to hear that this review was able to help you! We always try to explain everything very clearly on our reviews, and we tried taking you through the functions of each nutrient in EFX Sports’ Pyzme 5 fat burner.

      Let us know if we can help you in any other way. Keep lifting!

      Best regards,
      Team LeanBulking.com

  2. Hell Team LeanBulk.com. First, thanks for the review. But you are missing what Lyzme5 is all about. US Patent 9,216,160 which is the Lyzme5 ingredient. Would you be interested in a interview to discuss the science behind the product. Lyzme5 breaks up body fat and transports it into the blood stream so your body can burn fat (ketones) for energy. The rest of the formula is a thermo (no jitters).


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